ABSTRACT Many people argue that disagreements and inconsistencies between Research Ethics Committees are morally problematic and there has been much effort to ‘harmonise’ their judgements. Some inconsistencies are bad because they are due to irrationality, or carelessness, or the operation of conflicting interests, and so should be reduced or removed. Other inconsistencies, we argue, are not bad and should be left or even encouraged. In this paper we examine three arguments to reject the view that we should strive for complete (...) consistency between committees. The first argument is that differences in judgement are not necessarily incompatible with ideas of justice for patients who are potential participants of research reviewed by different committees. We call this ‘the justice argument.’ The second argument is that such committees do not have access to a single moral truth, to which their judgement is supposed to correspond. We call this the ‘moral pluralism argument.’ The third argument is that the process of ethics committee review is also morally relevant and not solely the outcome. We call this the ‘due process argument.’ While we fall short of establishing exactly how much variation and on what substantive issues would be ethically permissible, we show that it is largely inevitable and that a certain amount of variation could be seen as a desirable part of the institution of medical research. (shrink)

Sinking organic particles transfer ∼10 gigatonnes of carbon into the deep ocean each year, keeping the atmospheric CO2 concentration significantly lower than would otherwise be the case. The exact size of this effect is strongly influenced by biological activity in the ocean's twilight zone (∼50–1,000 m beneath the surface). Recent work suggests that the resident zooplankton fragment, rather than ingest, the majority of encountered organic particles, thereby stimulating bacterial proliferation and the deep‐ocean microbial food web. Here we speculate that this (...) apparently counterintuitive behaviour is an example of ‘microbial gardening’, a strategy that exploits the enzymatic and biosynthetic capabilities of microorganisms to facilitate the ‘gardener's’ access to a suite of otherwise unavailable compounds that are essential for metazoan life. We demonstrate the potential gains that zooplankton stand to make from microbial gardening using a simple steady state model, and we suggest avenues for future research. (shrink)

BackgroundPreprint usage is growing rapidly in the life sciences; however, questions remain on the relative quality of preprints when compared to published articles. An objective dimension of quality that is readily measurable is completeness of reporting, as transparency can improve the reader’s ability to independently interpret data and reproduce findings.MethodsIn this observational study, we initially compared independent samples of articles published in bioRxiv and in PubMed-indexed journals in 2016 using a quality of reporting questionnaire. After that, we performed paired comparisons (...) between preprints from bioRxiv to their own peer-reviewed versions in journals.ResultsPeer-reviewed articles had, on average, higher quality of reporting than preprints, although the difference was small, with absolute differences of 5.0% [95% CI 1.4, 8.6] and 4.7% [95% CI 2.4, 7.0] of reported items in the independent samples and paired sample comparison, respectively. There were larger differences favoring peer-reviewed articles in subjective ratings of how clearly titles and abstracts presented the main findings and how easy it was to locate relevant reporting information. Changes in reporting from preprints to peer-reviewed versions did not correlate with the impact factor of the publication venue or with the time lag from bioRxiv to journal publication.ConclusionsOur results suggest that, on average, publication in a peer-reviewed journal is associated with improvement in quality of reporting. They also show that quality of reporting in preprints in the life sciences is within a similar range as that of peer-reviewed articles, albeit slightly lower on average, supporting the idea that preprints should be considered valid scientific contributions. (shrink)

Americans’ excessive consumption of food harms their health and quality of life and also causes direct and indirect environmental degradation, through habitat loss and increased pollution from agricultural fertilizers and pesticides. We show here that reducing food consumption could improve Americans’ health and well-being while facilitating environmental benefits ranging from establishing new national parks and protected areas to allowing more earth-friendly farming and ranching techniques. We conclude by considering various public policy initiatives to lower per capita caloric intake and excessive (...) meat consumption, and to translate this temperate behavior into substantial environmental protection. (shrink)

Public health and service delivery programmes, interventions and policies are typically developed and implemented for the primary purpose of effecting change rather than generating knowledge. Nonetheless, evaluations of these programmes may produce valuable learning that helps determine effectiveness and costs as well as informing design and implementation of future programmes. Such studies might be termed ‘opportunistic evaluations’, since they are responsive to emergent opportunities rather than being studies of interventions that are initiated or designed by researchers. However, current ethical guidance (...) and registration procedures make little allowance for scenarios where researchers have played no role in the development or implementation of a programme, but nevertheless plan to conduct a prospective evaluation. We explore the limitations of the guidance and procedures with respect to opportunistic evaluations, providing a number of examples. We propose that one key missing distinction in current guidance is moral responsibility: researchers can only be held accountable for those aspects of a study over which they have control. We argue that requiring researchers to justify an intervention, programme or policy that would occur regardless of their involvement prevents or hinders research in the public interest without providing any further protections to research participants. We recommend that trial consent and ethics procedures allow for a clear separation of responsibilities for the intervention and the evaluation. (shrink)

In an attempt to learn from COVID-19, this essay features six responses to the question: what did COVID-19 teach us, expose in us, or purge out of us when it comes to spiritual formation in Christ? Each response was written independently of the others by one of the coauthors. Diane J. Chandler focuses in on how COVID-19 exposed grievous inequities for ethnic groups in the American church and broader society. Kelly M. Kapic reminds us of the goodness of human finitude (...) and how COVID restrictions have forced many of us to embrace our limitations. Siang-Yang Tan reflects on eight lessons he has learned during this pandemic year in his role shepherding a local church. James C. Wilhoit calls us to consider the structures that are needed for local church leadership to make wise and godly decisions in times of crisis. Richard Peace draws our attention to what might be learned from the forced monasticism brought about by COVID-19 quarantines. Finally, Ruth Haley Barton pauses to consider the interdependence of human life that has been dramatically illustrated by this pandemic. While these six responses certainly do not exhaust all there is for the church to learn from COVID, we present them in the spirit of “O Lord, teach us what we do not see” and hope they will inspire your own reflections. (shrink)

Objectives: To study the consent process experienced by participants who are enrolled in a molecular genetic research study that aims to find new genetic mutations responsible for an apparently inherited disorder.Design: Semi-structured interviews and analysis/description of main themes.Participants: 78 members of 52 families who had been recruited to a molecular genetic study.Results: People were well informed about the goals, risks and benefits of the genetic research study but could not remember the consent process. They had mostly been recruited to take (...) part by trusted clinicians or their relatives but had little memory of, or concern about signing consent forms. Families appeared to regard the research as a continuation of their, or their relatives’, clinical care.Conclusions: Ethical review should be more flexible in its attitude to consent forms and written information sheets for some sorts of research. For rare genetic disease studies where research has been discussed fully within the clinical setting then the consent obtained at that time could suffice rather than needing extra consent at a later stage. However, clinician-researchers will need to ensure that their duty of care extends for the duration of the research and beyond. (shrink)

The role of imagery in encoding event-based prospective memories has yet to be fully clarified. Herein, it is argued that imagery augments a cue-to-context association that supports event-based prospective memory performance. By this account, imagery encoding not only improves prospective memory performance but also reduces interference to intention-related information that occurs outside of context. In the current study, when lure words occurred outside of the appropriate responding context, the use of imagery encoding strategies resulted in less interference when compared with (...) a standard event-based intention condition. This difference was eliminated when participants were not given a specific context to associate their intention . These results support a cue-to-context association account of how imagery operates in certain event-based prospective memory tasks. (shrink)

Analyses of between-sex differences have provided a powerful starting point for evolutionarily informed work on human sexuality. This early work set the stage for an evolutionary analysis of within-sex differences in human sexuality. A comprehensive theory of human sexual strategies must address both between-sex differences and within-sex differences in evolved psychology and manifest behavior.

I defend mereological nihilism, the view that there are no composite objects, against a challenge from ontological emergence, the view that some things have properties that are ‘something over and above’ the properties of their parts. As the nihilist does not believe in composite wholes, there is nothing in the nihilist's ontology to instantiate emergent properties – or so the challenge goes. However, I argue that some simples can collectively instantiate an emergent property, so the nihilist's ontology can in fact (...) accommodate emergent properties. Furthermore, I show that employing plural instantiation does not bloat the nihilist's ontology or ideology. (shrink)

The language of “participant-driven research,” “crowdsourcing” and “citizen science” is increasingly being used to encourage the public to become involved in research ventures as both subjects and scientists. Originally, these labels were invoked by volunteer research efforts propelled by amateurs outside of traditional research institutions and aimed at appealing to those looking for more “democratic,” “patient-centric,” or “lay” alternatives to the professional science establishment. As mainstream translational biomedical research requires increasingly larger participant pools, however, corporate, academic and governmental research programs (...) are embracing this populist rhetoric to encourage wider public participation. We examine the ethical and social implications of this recruitment strategy. We begin by surveying examples of “citizen science” outside of biomedicine, as paradigmatic of the aspirations this democratizing rhetoric was originally meant to embody. Next, we discuss the ways these aspirations become articulated in the biomedical context, with a view to drawing out the multiple and potentially conflicting meanings of “public engagement” when citizens are also the subjects of the science. We then illustrate two uses of public engagement rhetoric to gain public support for national biomedical research efforts: its post-hoc use in the “care.data” project of the National Health Service in England, and its proactive uses in the “Precision Medicine Initiative” of the United States White House. These examples will serve as the basis for a normative analysis, discussing the potential ethical and social ramifications of this rhetoric. We pay particular attention to the implications of government strategies that cultivate the idea that members of the public have a civic duty to participate in government-sponsored research initiatives. We argue that such initiatives should draw from policy frameworks that support normative analysis of the role of citizenry. And, we conclude it is imperative to make visible and clear the full spectrum of meanings of “citizen science,” the contexts in which it is used, and its demands with respect to participation, engagement, and governance. (shrink)

Cognitive Science, Volume 46, Issue 6, June 2022.

This book, a member of the Series in Affective Science, is a unique interdisciplinary sequence of articles on the cognitive neuroscience of emotion by some of ...

Elephants show a rich social organization and display a number of unusual traits. In this paper, we analyse reports collected over a thirty-five year period, describing behaviour that has the potential to reveal signs of empathic understanding. These include coalition formation, the offering of protection and comfort to others, retrieving and 'babysitting' calves, aiding individuals that would otherwise have difficulty in moving, and removing foreign objects attached to others. These records demonstrate that an elephant is capable of diagnosing animacy and (...) goal directedness, and is able to understand the physical competence, emotional state and intentions of others, when they differ from its own. We argue that an empathic understanding of others is the simplest explanation of these abilities, and discuss reasons why elephants appear to show empathy more than other non-primate species. (shrink)

J. L. Austin, in "Ifs and Cans," proclaimed the common hope that we soon "may see the birth, through the joint labors of philosophers, grammarians, and numerous other students of language, of a true and comprehensive science of language." The problem has always been with the "joint labors" part. Philosophers have always been willing to issue linguists dictums and linguists have been happy to teach philosophers "plain facts." Austin’s general view of language, and his particular notion of performative utterance, can (...) be found in the writing of J. R. Firth, the most commanding British linguist of Austin’s generation, but Austin never refers to Firth. In the present volume, however, we find clear and exciting evidence of genuinely joint labors on the part of philosophers and linguists. They stem from a summer conference in 1969 rounded out with contributions from notables. To two thick issues of Synthese the editors have added a dazzling piece by Saul Kripke, two substantial pieces by James McCawley and J. R. Ross, a short paper by Paul Ziff, and a reprint of P. F. Strawson’s "Grammar and Philosophy." This is an invaluable book and the best book among the many now available concerning the interaction of linguistics and philosophy: worth the cost, which the contributors attempted to reduce through foregoing royalties. The philosophers in this volume hold, or hold intriguing, the view that the semantics of a natural language can and must, in effect, be a theory of truth for a language in much the manner that Tarski suggested, and provided, for artificial language: the recursive specification of biconditionals in which the left hand gives the structural description of an object language sentence and the right hand, the truth conditions in the metalanguage. In "homophonic" translation this requirement can be trivially satisfied simply by mentioning the sentence on the left that one uses on the right: one makes the requirement non-trivial by forcing enough into the recursive specification so that one captures the native speaker’s implicit semantic competence. In this volume, the "orthodox" Davidsonian program, which takes the syntax of the metalanguage to be standard predicate logic, is ably argued by John Wallace ; Richard Montague, David Lewis, and Jaakko Hintikka would want an intensional logic covering modality and propositional attitudes. The linguists who find this philosophical climate most appealing are called "generative semanticists": McCawley, Ross, George Lakoff and others argue that any proposed semantic rule will eventually prove necessary to syntax too and that, hence, the deepest level of syntactical form will be equivalent to semantic form. Whatever the ultimate fate of this joint program, it leads here to much exciting interaction between linguists and philosophers: linguists who welcome the machinery and conceptual standards of modern logic, and philosophers who try to grasp the specifics of crucial issues in recent linguistic theory. Even if Quine’s doubts, here sketched, and Chomsky’s currently unpublished more technical objections should be well-founded, nonetheless the joint labor will have been very much worthwhile. Aside from this general debate about semantics, there are several papers covering more specific issues. The papers of J. A. Fodor, Terence Parsons, and Ross concern adverbs and the logical form of action sentences; several papers, particularly B. H. Partee’s, examine "Opacity, Coreference, and Pronouns." In all these papers one notes the fulfillment of Austin’s hope that philosophic and linguistic arguments should become intermixed, if not at times properly indistinguishable. Perhaps the most enjoyable and exciting paper stands aside from linguistics: Saul Kripke’s "Naming and Necessity." Kripke here argues quite informally for the separation of analytic, a priori, and necessary that is required for a Kripke style, S5, modal logic with de re modalities. "Gold is a yellow metal," for example, turns out to be contingent, while "Heat is the motion of particles" is necessary but a posteriori ; and that philosopher’s stone of stones, "The morning star is the evening star," is discovered to be necessary but a posteriori.—J. L. (shrink)

Elephants show a rich social organization and display a number of unusual traits. In this paper, we analyse reports collected over a thirty-five year period, describing behaviour that has the potential to reveal signs of empathic understanding. These include coalition formation, the offering of protection and comfort to others, retrieving and 'babysitting' calves, aiding individuals that would otherwise have difficulty in moving, and removing foreign objects attached to others. These records demonstrate that an elephant is capable of diagnosing animacy and (...) goal directedness, and is able to understand the physical competence, emotional state and intentions of others, when they differ from its own. We argue that an empathic understanding of others is the simplest explanation of these abilities, and discuss reasons why elephants appear to show empathy more than other non-primate species. (shrink)

This collection, with an agreeable proportion of new material and a sensible selection of old, is worth the money and ought to be on the shelf of anyone interested in recent work on language by philosophers, psychologists, and linguists. The section by linguists proper is the longer and more up to date but this seems quite in order: today neither work in philosophy nor psychology can provide a plausible center-of-attention that will take in the other and linguistics as flanking material. (...) For better and worse linguistics is the centerpiece: and the debate between "interpretive" and "generative" semanticists, here respectively represented by Chomsky and George Lakoff, is the center, most likely, of the centerpiece. The generative semanticists suggest that the base and semantic components ultimately come to the same: the distinction between syntactic rules and semantic rules is presumed as in the Chomskian position but it is thought that the algorithm of wellformedness will turn out to provide all the rules needed for semantic interpretation. The interpretive semantic alternative, here argued by Chomsky in a paper otherwise difficult to obtain except in mimeo, distinguishes semantic from base component by insisting, particularly in matters respecting reference and quantification, that transformations are not meaning-invariant, and that, hence, the semantic component is fed by both the base and surface structures independently. To put the interpretive view in terms of Tarski-cum-Davidsonian biconditionals, we would no longer have on the left side of the biconditional one ’structural-descriptive’ string but rather two separate strings, one surface and the other deep, that would jointly and independently determine meaning. The generative semanticists, following James McCawley, stress that their argument against autonomous deep syntax follows in form Morris Halle’s well-known argument against a phonemic level of description supposed intermediate between superficial surface syntax and systematic phonetics. The basic question one raises against this argument is whether logico-semantic form constitutes itself for linguistic science as one level of description and as an essentially linguistic level of description. One can see an obvious place for philosophers in these arguments, though one finds in this volume very little suggestion of philosophical-semantic work, in the Frege-Carnap tradition, that Donald Davidson, Richard Montague, John Wallace, etc., have been carrying on lately. There is a previously unpublished paper by David Wiggins in this vein, but though Wiggins is his usual brilliant and playfully convoluted self, this is too idiosyncratic and occasional a piece to represent what is by way of a movement. Indeed, aside from the Wiggins-Alston material, the philosopher’s section is solid but familiar material: H. P. Grice’s famous paper on meaning and Paul Ziff’s criticism of Grice’s theory; Gilbert Harman’s "Three Levels of Meaning"; late-1960s papers by Donnellan, Linsky, Quine, Strawson, Vendler, and Searle on reference. But this aside this volume vividly makes the point that philosophy and linguistics have never been more entangled with each other in a genuine working relationship. Chomsky’s arguments come in part from recent philosopher’s work. There is evident concern by linguists with presuppositions and performatives. "Fact," an important and not easily available paper by Paul and Carol Kilparski, sparks the philosophic imagination—as do new pieces on lexical entries, semantic features, and categories by Charles Fillmore, Manfried Bierwisch, and others. Almost enough to justify J. L. Austin’s hopes for a joint endeavor of linguists, philosophers, and psychologists: one sees in the footnotes and bibliographies, in the issue and vocabulary, that disciplines are joining and reflecting upon each other in day-to-day work. The psychology section also contains one large new piece: a splendidly energetic defense of linguistic behaviorism by Charles Osgood. One finds balance for this in Jerry Fodor’s "Could meaning be an rm?" And some good, current, and often not easily available material by George Miller, Eric Lennberg, and others. The "overviews" for the various sections are quite distinguished themselves: but this is only in keeping with general character of this reader.—J. L. (shrink)

The language of “participant-driven research,” “crowdsourcing” and “citizen science” is increasingly being used to encourage the public to become involved in research ventures as both subjects and scientists....

This is a descriptive study which examined the attitudes and perceptions of 273 business students at eight universities across the U.S. towards ethics education. The results indicate that students perceive that the level of discussion of ethics and ethical issues ranges from less than adequate in some marketing courses to adequate in others. Sales/sales management courses received the highest ratings for coverage of ethical issues, while transportation/logistics courses scored the lowest.The study also finds that students believe, quite strongly, that the (...) discussion of ethics and ethical issues is worthwhile and important. Many feel a course in business/marketing ethics should be required and more indicate that they would take such a course, if offered, even if it was not required. (shrink)